Singapore pharmacy body issues counselling standards for liraglutide initiation
The evidence base is thin and the document says so, which is to its credit.
TheCompound Journal
Reporting on incretins, compounding & the peptide supply chain
Page 4 of 5 of this archive, newest first.
The evidence base is thin and the document says so, which is to its credit.
A proper account of an operation that existed, and of what closing it cost.
Efficacy was never the question in this appraisal. Duration of treatment was.
A result on one vial generalises to a batch only if the vial was drawn in a way that makes it representative — and nobody records how it was drawn.
A flag is a probability statement about a population. It is not a statement about the person holding the printout.
Reported from the sessions, and from the two hours afterwards.
The document is four pages. Three of them are about dates.
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
A reminder that a purity figure is the output of a method, and that methods differ.
What adding GIP activity does, on the current evidence, and what remains unresolved.
A stability programme needs a protocol, defined conditions, a stability-indicating method and time. Time is the ingredient no commercial testing service can sell.
A proper account of an operation that existed, and of what closing it cost.
The route did not close because of a rule about peptides.
A design note rather than a result: what the comparator was, and what that permits you to conclude.
A reminder that a purity figure is the output of a method, and that methods differ.
Constipation is the most tractable of the effects and the most consistently under-managed.
Our position is about documentation practice. It is not an allegation about anybody’s honesty, and we are explicit about the difference.
A drug that delays gastric emptying complicates the assumption behind every fasting instruction in perioperative medicine. The professional bodies have moved twice on this…
Follow the resin, not the catalogue.
Follow the resin, not the catalogue.
The report states the gradient, the wavelength and the integration threshold, which is more than most.
Every withdrawal trial compared full dose against nothing. The clinically interesting comparison — full dose against a reduced one — has not been randomised.
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
The evidence base is thin and the document says so, which is to its credit.
Reported from the sessions, and from the two hours afterwards.
Reported from the analysis, not from a warning notice.
The purity figure is the least informative line on a well-constructed certificate and the only line most buyers read.
The trials measured mass. Nobody measured whether the participants got weaker.
Follow the resin, not the catalogue.
The evidence base is thin and the document says so, which is to its credit.
The observation that closes a facility is rarely the dramatic one.
The result is unremarkable. What the report omits is not.
What the published pharmacokinetics permit, what the labels state, and where the two diverge.
What was pre-specified, what was exploratory, and what was calculated afterwards by people who did not run the trial.
A proper account of an operation that existed, and of what closing it cost.
The document is four pages. Three of them are about dates.
Reported from the analysis, not from a warning notice.
The receptor populations that produce satiety and the ones that produce nausea overlap substantially. That is why the ceiling of this drug class is where it is, and it is…
Bacterial endotoxin is a heat-stable lipopolysaccharide from the outer membrane of Gram-negative organisms. It survives sterilisation, passes a sterilising filter, and is…
Reported from the sessions, and from the two hours afterwards.