Side effects, cost, supply, target: four reasons with four trajectories
A supply interruption is a discontinuation with no notice, no taper and no plan. That is a distinct clinical situation.
The archive
Page 100 of 170 of this archive, newest first.
The consolidator trading as Meridian Freight Partners closes after 23 years
A proper account of an operation that existed, and of what closing it cost.
Holograms, QR codes and other things that are not verification
Reported from the analysis, not from a warning notice.
What a 41% rise in coupling-reagent prices does to a 5 mg vial
Follow the resin, not the catalogue.
A shortage listing ends. 18 pharmacies now have a business model and no legal basis for it.
The document is four pages. Three of them are about dates.
Everything on the page, in the order a chemist would read it
The purity figure is the least informative line on a well-constructed certificate and the only line most buyers read.
New Zealand health authority warns on falsified tirzepatide pens
Reported from the analysis, not from a warning notice.
SUSTAIN-6 misses on a secondary endpoint the coverage has not mentioned
A design note rather than a result: what the comparator was, and what that permits you to conclude.
What the new the Netherlands guidance says about stopping
The evidence base is thin and the document says so, which is to its credit.
LAL, kinetic chromogenic, recombinant factor C: three ways to the same figure
Three compendial method families are in routine use and a fourth, based on a recombinant enzyme rather than crab lysate, is now compendial in its own right.
HbA1c and its lag: what a result three months old is telling you
A robust, cheap, standardised assay with a specific and well-catalogued set of failure modes, several of which are common in this population.
ERP declines, for the 3rd time, to name its synthesis house
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
Independent analysis puts a SSA survodutide lot at 97.1%, against 96.4% on the certificate
The result is unremarkable. What the report omits is not.
A shortage listing ends. 16 pharmacies now have a business model and no legal basis for it.
The document is four pages. Three of them are about dates.
The slide that was not in the abstract
Reported from the sessions, and from the two hours afterwards.
Why a result on one vial says less than the trade needs it to
What a laboratory can and cannot know about the provenance, storage history and representativeness of what lands on its bench.
What the trials counted as intolerance
We set out the questions that distinguish a symptom to manage from a dose to change.
What a 32% rise in coupling-reagent prices does to a 30 mg vial
Follow the resin, not the catalogue.
Medutest result on a Nantong semaglutide lot lands 3.0 points below the supplier’s figure
The Journal submitted the sample and paid for the analysis. The vendor was told in advance.
From the floor in Zhuhai: 20 posters, one theme
Reported from the sessions, and from the two hours afterwards.
Why summer is a documented quality problem in this trade
The route did not close because of a rule about peptides.
The last mile is the warmest mile
The honest finding is more nuanced than the alarm: a lyophilised cake tolerates a brief warm excursion far better than a reconstituted solution does, and the trade’s real…
The site you keep using is the site that stops working
Lipohypertrophic tissue is less painful to inject into, which is precisely why people keep injecting into it.
Independent analysis puts a QSC exenatide lot at 97.5%, against 96.7% on the certificate
The supplier has not disputed the finding. It has not explained the gap either.
The slide that was not in the abstract
Reported from the sessions, and from the two hours afterwards.
New Zealand pharmacy body issues counselling standards for liraglutide initiation
The evidence base is thin and the document says so, which is to its credit.
The interventions with trial support, and the much longer list without
Almost nothing in the standard management repertoire has been tested in a randomised trial in this specific population. We say what is extrapolated and from where.
Why your laboratory interval differs from the one in the textbook
A flag is a probability statement about a population. It is not a statement about the person holding the printout.
Sending the same vial twice, under two names
The Journal submitted split samples from single lots to three assay services, under names unconnected to this publication, and published each method alongside each result.
The consolidator trading as Meridian Freight Partners enters a consent decree and stops sterile preparation
The observation that closes a facility is rarely the dramatic one.