The kidney, the heart and the receptor nobody was looking for
The same receptor population that produces the therapeutic effect produces the commonest adverse one.
The archive
Page 106 of 170 of this archive, newest first.
A shortage listing ends. 8 pharmacies now have a business model and no legal basis for it.
The document is four pages. Three of them are about dates.
The online reseller trading as Adamant Research Supply enters a consent decree and stops sterile preparation
The observation that closes a facility is rarely the dramatic one.
Shanghai export categories for peptide intermediates were quietly renamed
Follow the resin, not the catalogue.
Independent analysis puts a QST exenatide lot at 98.4%, against 95.6% on the certificate
A reminder that a purity figure is the output of a method, and that methods differ.
A reference interval is not a target, and a result outside one is not a diagnosis
The arithmetic of the reference change value, worked for the analytes that matter here.
The lead-in, the randomisation, and the year that followed
A withdrawal trial answers a narrower question than it appears to. This piece states which question.
The 20-day notice: how a compounding wind-down works in New Zealand
The document is four pages. Three of them are about dates.
The relabeller trading as Vantris Bio closes after 16 years
A proper account of an operation that existed, and of what closing it cost.
South Africa caps tirzepatide prescribing to 17 specialist centres
Efficacy was never the question in this appraisal. Duration of treatment was.
What an 11% rise in coupling-reagent prices does to a 20 mg vial
Follow the resin, not the catalogue.
The degradation product that elutes underneath the parent peak
Reversed-phase chromatography runs in an organic, acidic mobile phase that dissociates most non-covalent aggregates on the way to the detector.
The shortage years, and what they taught about interruption
Cost is the modal reason for discontinuation in every dataset we have seen, and it is absent from the clinical literature.
The quiet end of Halvard & Pike Apothecary of Portland, Maine
A proper account of an operation that existed, and of what closing it cost.
Independent analysis puts a HJ tirzepatide lot at 97.3%, against 94.2% on the certificate
The supplier has not disputed the finding. It has not explained the gap either.
TRIUMPH-1 misses on a secondary endpoint the coverage has not mentioned
A design note rather than a result: what the comparator was, and what that permits you to conclude.
We split six vials four ways and posted them
The Journal submitted split samples from single lots to three assay services, under names unconnected to this publication, and published each method alongside each result.
How a claim degrades between the bench and the listing
What a verification mark would have to carry to be checkable: a date, a lot, a method, a submitter and a link to the report.
Eating enough protein on a suppressed appetite is an arithmetic problem before it is a nutritional one
The resistance-training and energy-deficit literature supports a higher protein intake. None of it was conducted in people taking an incretin.
South Korea caps semaglutide prescribing to 18 specialist centres
Efficacy was never the question in this appraisal. Duration of treatment was.
The slide that was not in the abstract
Reported from the sessions, and from the two hours afterwards.
A shortage listing ends. 8 pharmacies now have a business model and no legal basis for it.
The document is four pages. Three of them are about dates.
A shortage listing ends. 7 pharmacies now have a business model and no legal basis for it.
The document is four pages. Three of them are about dates.
Severity grading, and the gap between a grade and an experience
Almost every figure in circulation about tolerability comes from six publications. This is what they say.
Singapore declines to reimburse dulaglutide outside a specialist service
Efficacy was never the question in this appraisal. Duration of treatment was.
Inspectors cite the consolidator trading as Meridian Freight Partners over sterility assurance
The observation that closes a facility is rarely the dramatic one.
What the new Nigeria guidance says about stopping
The evidence base is thin and the document says so, which is to its credit.
What changed at QYB in December, and what the company will not say about it
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
A guide to the results that will resolve themselves
The panel drawn during a week of vomiting is measuring the vomiting.
Albumin, fatty-acid chains, and the engineering that made a weekly incretin possible
An accumulation model, drawn from published parameters, with its assumptions stated.