Why "muscle-sparing" is a marketing term and not a measurement
The rule that a quarter of weight lost is lean tissue has been in textbooks for decades and does not survive close reading.
The archive
Page 117 of 170 of this archive, newest first.
Why summer is a documented quality problem in this trade
The route did not close because of a rule about peptides.
What changed at SGN in October, and what the company will not say about it
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
Switzerland caps dulaglutide prescribing to 15 specialist centres
Efficacy was never the question in this appraisal. Duration of treatment was.
The quiet end of Halvard & Pike Apothecary of Portland, Maine
A proper account of an operation that existed, and of what closing it cost.
Weight regain is not a failure of willpower and it is not a mystery
The variance around the mean regain trajectory is large and unexplained, exactly as it is for the weight loss.
LEADER misses on a secondary endpoint the coverage has not mentioned
A design note rather than a result: what the comparator was, and what that permits you to conclude.
Portugal health authority warns on falsified semaglutide pens
Reported from the analysis, not from a warning notice.
The online reseller trading as Adamant Research Supply closes after 5 years
A proper account of an operation that existed, and of what closing it cost.
The GLP-1 receptor is not a switch, and retatrutide is not a key
Receptor pharmacology explains more of the clinical picture than the dose does — and almost none of it appears in the material patients are given.
Check the vial, not the box
A document is only as good as the chain that connects it to the material, and most chains here are two or three links longer than the paperwork admits.
Holograms, QR codes and other things that are not verification
Reported from the analysis, not from a warning notice.
What a 32% rise in coupling-reagent prices does to a 15 mg vial
Follow the resin, not the catalogue.
The slide that was not in the abstract
Reported from the sessions, and from the two hours afterwards.
A shortage listing ends. 20 pharmacies now have a business model and no legal basis for it.
The document is four pages. Three of them are about dates.
Is survodutide better than retatrutide, or differently balanced?
Head-to-head data exists for some of these comparisons and not for others. This piece says which.
The label says four weeks. The clinic says whatever holds.
The published ladder exists because a protocol needed a single number. Practice has never followed it exactly, and the regulatory file never assumed it would.
India health authority warns on falsified semaglutide pens
Reported from the analysis, not from a warning notice.
Xianning export categories for peptide intermediates were quietly renamed
Follow the resin, not the catalogue.
A shortage listing ends. 18 pharmacies now have a business model and no legal basis for it.
The document is four pages. Three of them are about dates.
Halvard & Pike Apothecary of Portland, Maine enters a consent decree and stops sterile preparation
The observation that closes a facility is rarely the dramatic one.
What a split-sample exercise can establish, and what it cannot
Duplicate submissions under different names test within-laboratory repeatability, which is a different quantity from between-laboratory reproducibility.
A part per million, in context
Every instrument specification quoted in an advertisement is a best case obtained on a calibration mixture, not on a submitted vial.
SURPASS-3 extension data: what happens after the trial stops
A design note rather than a result: what the comparator was, and what that permits you to conclude.
The 12-day notice: how a compounding wind-down works in Germany
The document is four pages. Three of them are about dates.
From the floor in Wuhan: 24 posters, one theme
Reported from the sessions, and from the two hours afterwards.
Discontinuation rates, read honestly
Trial discontinuation figures are a floor, not an estimate: trial populations are supported in ways ordinary patients are not.
The badge economy, and what it is actually certifying
Every step between the laboratory report and the product page removes information, and the badge is the last step.
The out-of-range flag is a statistical convention with a printer attached
A flag is a probability statement about a population. It is not a statement about the person holding the printout.
What the new Germany guidance says about stopping
The evidence base is thin and the document says so, which is to its credit.