What a 21% rise in coupling-reagent prices does to a 5 mg vial
Follow the resin, not the catalogue.
TheCompound Journal
Reporting on incretins, compounding & the peptide supply chain
Page 148 of 170 of this archive, newest first.
Follow the resin, not the catalogue.
The evidence base is thin and the document says so, which is to its credit.
The observation that closes a facility is rarely the dramatic one.
We set out the questions that distinguish a symptom to manage from a dose to change.
A 4 mm needle at ninety degrees without a skin pinch is adequate for essentially all adults. The persistence of 12.7 mm needles in this market is habit, not reasoning.
A result on one vial generalises to a batch only if the vial was drawn in a way that makes it representative — and nobody records how it was drawn.
Reported from the analysis, not from a warning notice.
A design note rather than a result: what the comparator was, and what that permits you to conclude.
The evidence base is thin and the document says so, which is to its credit.
A proper account of an operation that existed, and of what closing it cost.
Trial adverse-event tables count episodes reported to a study nurse. They are the best data we have and they systematically under-record the mundane.
A design note rather than a result: what the comparator was, and what that permits you to conclude.
The route did not close because of a rule about peptides.
Reported from the sessions, and from the two hours afterwards.
Degradation rates rise exponentially with temperature while an arithmetic mean adds linearly. Mean kinetic temperature is the weighting that reconciles the two, and it is…
A peptide has a monoisotopic mass and an average mass, they differ by several daltons at this molecular size, and a certificate that does not say which it quotes cannot be…
Follow the resin, not the catalogue.
The document is four pages. Three of them are about dates.
A proper account of an operation that existed, and of what closing it cost.
A reminder that a purity figure is the output of a method, and that methods differ.
The evidence on stopping is better than the evidence on almost anything else in this field, because somebody deliberately randomised it.
Duplicate submissions under different names test within-laboratory repeatability, which is a different quantity from between-laboratory reproducibility.
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
The document is four pages. Three of them are about dates.
A proper account of an operation that existed, and of what closing it cost.
Efficacy was never the question in this appraisal. Duration of treatment was.
We work through a single chromatogram twice, under two integration conventions, and show where the difference comes from.
Cost is the modal reason for discontinuation in every dataset we have seen, and it is absent from the clinical literature.
A design note rather than a result: what the comparator was, and what that permits you to conclude.
The document is four pages. Three of them are about dates.