Independent analysis puts a MKM dulaglutide lot at 99.2%, against 96.7% on the certificate
The report states the gradient, the wavelength and the integration threshold, which is more than most.
The archive
Page 74 of 170 of this archive, newest first.
The convention nobody explains before handing over the vial
Insulin syringes are graduated in units on a convention that fixes 100 units to one millilitre. That convention says nothing about how much peptide is in a unit, and…
The figure of merit this trade chose, and the four it did not
A market that competes on one measurement will optimise that measurement. There are legitimate ways to raise a purity figure that involve no change to the product at all.
Janoshik result on a Nantong mazdutide lot lands 0.9 points below the supplier’s figure
The result is unremarkable. What the report omits is not.
What a 26% rise in coupling-reagent prices does to a 20 mg vial
Follow the resin, not the catalogue.
FLOW extension data: what happens after the trial stops
A design note rather than a result: what the comparator was, and what that permits you to conclude.
Janoshik result on a Wuxi semaglutide lot lands 2.4 points below the supplier’s figure
The supplier has not disputed the finding. It has not explained the gap either.
The lead-in, the randomisation, and the year that followed
A withdrawal trial answers a narrower question than it appears to. This piece states which question.
Hydrolysis, isomerisation, and the arithmetic of a broken bond
Deamidation, oxidation, aggregation and hydrolysis account for nearly all of what happens to a peptide over time. Each has a characteristic residue, a characteristic…
Independent analysis puts a SGN orforglipron lot at 96.1%, against 93.2% on the certificate
The result is unremarkable. What the report omits is not.
GGPeps declines, for the 15th time, to name its synthesis house
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
A shortage listing ends. 13 pharmacies now have a business model and no legal basis for it.
The document is four pages. Three of them are about dates.
The quiet end of Calder Vale Peptides of Skipton
A proper account of an operation that existed, and of what closing it cost.
What we asked twenty suppliers about stability data
A retest date says that material should be re-examined before use. An expiry date says it should not be used. The trade uses the second word for the first concept.
Deamidation, oxidation, and the two shifts worth memorising
What would be needed to catch each of these, and what it would cost.
Escalating onto a rising curve
The four-week step exists because four to five weeks is approximately how long a once-weekly drug takes to stop rising at a fixed dose. That is a good reason, and it is not…
VendorInvestigate result on a Shanghai mazdutide lot lands 2.8 points below the supplier’s figure
The supplier has not disputed the finding. It has not explained the gap either.
What changed at FGP in June, and what the company will not say about it
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
Why summer is a documented quality problem in this trade
The route did not close because of a rule about peptides.
Inspectors cite the consolidator trading as Meridian Freight Partners over sterility assurance
The observation that closes a facility is rarely the dramatic one.
Holding a dose is a decision, not a failure
Every major phase 3 protocol in this class allowed escalation to be delayed for tolerability. Almost no product label explains the mechanics of doing so.
From the floor in Shanghai: 7 posters, one theme
Reported from the sessions, and from the two hours afterwards.
Mexico declines to reimburse semaglutide outside a specialist service
Efficacy was never the question in this appraisal. Duration of treatment was.
FGP declines, for the 16th time, to name its synthesis house
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
The shortage years, and what they taught about interruption
Cost is the modal reason for discontinuation in every dataset we have seen, and it is absent from the clinical literature.
Twenty-eight days is a number from somebody else’s product
Every degradation pathway accelerates by orders of magnitude on reconstitution, because the solvent that lyophilisation removed is the reagent most of them need.
The slide that was not in the abstract
Reported from the sessions, and from the two hours afterwards.
Holograms, QR codes and other things that are not verification
Reported from the analysis, not from a warning notice.
What changed at KP in May, and what the company will not say about it
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
Why summer is a documented quality problem in this trade
The route did not close because of a rule about peptides.