Accuracy, precision and the tolerance nobody states
Parts per million sound impressive until they are converted into daltons at the molecular weight of the thing being measured.
Certificates of analysis
What a COA contains, what it omits, how to read one, and how to tell a real one from a template.
The named comparison we promised two years ago
Two years ago we ran an anonymised version of this comparison and promised a named one. This is it, with every method printed in full.
What changed at SWB in June, and what the company will not say about it
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
Hydrolysis, isomerisation, and the arithmetic of a broken bond
An isoaspartate rearrangement changes the molecule and not the mass. A method that confirms identity by molecular weight alone will report it as the parent compound.
SGN declines, for the 21st time, to name its synthesis house
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
Holograms, QR codes and other things that are not verification
Reported from the analysis, not from a warning notice.
Janoshik result on a Qingdao semaglutide lot lands 3.7 points below the supplier’s figure
A reminder that a purity figure is the output of a method, and that methods differ.
Twelve things a real certificate has, and what their absence means
Nothing on this page is difficult. It is simply unfamiliar, and unfamiliarity is what makes a weak certificate look like a strong one.
BCH declines, for the 17th time, to name its synthesis house
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
Independent analysis puts a FGP exenatide lot at 95.7%, against 94.1% on the certificate
The report states the gradient, the wavelength and the integration threshold, which is more than most.
Holograms, QR codes and other things that are not verification
Reported from the analysis, not from a warning notice.
Saudi Arabia health authority warns on falsified tirzepatide pens
Reported from the analysis, not from a warning notice.
One method is one opinion
Aggregates dissociate in the mobile phase and are recorded as monomer. Only a size-based separation reports them.
Australia health authority warns on falsified liraglutide pens
Reported from the analysis, not from a warning notice.
What changed at FGP in June, and what the company will not say about it
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
What a split-sample exercise can establish, and what it cannot
Duplicate submissions under different names test within-laboratory repeatability, which is a different quantity from between-laboratory reproducibility.
Norway health authority warns on falsified liraglutide pens
Reported from the analysis, not from a warning notice.
What changed at SWB in June, and what the company will not say about it
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
What a laboratory knows about the material it receives
Chain of custody, in a regulated setting, begins at sampling. Here it begins when the package arrives.
Two per cent water sounds like nothing and is not nothing
Residual moisture is measured routinely in regulated manufacture, is reported almost nowhere in this trade, and predicts long-term stability better than any other single…