Accuracy, precision and the tolerance nobody states
Parts per million sound impressive until they are converted into daltons at the molecular weight of the thing being measured.
Peptide synthesis
Solid-phase and hybrid routes, coupling chemistry, protecting-group strategy, and the economics of chain length.
What a 28% rise in coupling-reagent prices does to a 10 mg vial
Follow the resin, not the catalogue.
Wuhan export categories for peptide intermediates were quietly renamed
Follow the resin, not the catalogue.
Nantong export categories for peptide intermediates were quietly renamed
Follow the resin, not the catalogue.
Why a 0.036-dalton difference is the hardest number in peptide identity
Every instrument specification quoted in an advertisement is a best case obtained on a calibration mixture, not on a submitted vial.
Changsha export categories for peptide intermediates were quietly renamed
Follow the resin, not the catalogue.
Nantong export categories for peptide intermediates were quietly renamed
Follow the resin, not the catalogue.
Hong Kong export categories for peptide intermediates were quietly renamed
Follow the resin, not the catalogue.
What a 37% rise in coupling-reagent prices does to a 20 mg vial
Follow the resin, not the catalogue.
Suzhou export categories for peptide intermediates were quietly renamed
Follow the resin, not the catalogue.
What a 15% rise in coupling-reagent prices does to a 5 mg vial
Follow the resin, not the catalogue.
Guangzhou export categories for peptide intermediates were quietly renamed
Follow the resin, not the catalogue.
Chengdu export categories for peptide intermediates were quietly renamed
Follow the resin, not the catalogue.
What a 26% rise in coupling-reagent prices does to a 20 mg vial
Follow the resin, not the catalogue.
When a better instrument changes the answer rather than the confidence
Calibration drift is real, unremarkable, and the reason serious laboratories run internal standards.
Xianning export categories for peptide intermediates were quietly renamed
Follow the resin, not the catalogue.
What a 37% rise in coupling-reagent prices does to a 5 mg vial
Follow the resin, not the catalogue.
Hong Kong export categories for peptide intermediates were quietly renamed
Follow the resin, not the catalogue.
What a 42% rise in coupling-reagent prices does to a 15 mg vial
Follow the resin, not the catalogue.
Carbon-13, and the reason a peptide has more than one mass
A peptide has a monoisotopic mass and an average mass, they differ by several daltons at this molecular size, and a certificate that does not say which it quotes cannot be…