What changed at QST in January, and what the company will not say about it
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
The archive
Page 166 of 170 of this archive, newest first.
Why the bone question is harder than the muscle question
Weight loss reduces bone mineral density at load-bearing sites. Whether that translates into fractures in this population is unmeasured.
Why receptor selectivity is the least discussed number in incretin pharmacology
Selectivity, potency and efficacy are three different measurements. The trade routinely reports none of them.
How a claim degrades between the bench and the listing
The Journal does not treat a badge as evidence and states so wherever it reports one.
Calder Vale Peptides of Skipton closes after 5 years
A proper account of an operation that existed, and of what closing it cost.
What the new Turkey guidance says about stopping
The evidence base is thin and the document says so, which is to its credit.
Wuhan export categories for peptide intermediates were quietly renamed
Follow the resin, not the catalogue.
Denmark health authority warns on falsified semaglutide pens
Reported from the analysis, not from a warning notice.
Resolving power and mass accuracy are two different specifications
Every instrument specification quoted in an advertisement is a best case obtained on a calibration mixture, not on a submitted vial.
Why summer is a documented quality problem in this trade
The route did not close because of a rule about peptides.
The consolidator trading as Meridian Freight Partners closes after 9 years
A proper account of an operation that existed, and of what closing it cost.
What changed at WWB in January, and what the company will not say about it
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
Holograms, QR codes and other things that are not verification
Reported from the analysis, not from a warning notice.
Why people actually stop, in the order they actually stop
Cost is the modal reason for discontinuation in every dataset we have seen, and it is absent from the clinical literature.
Site selection when the tissue has already changed
A rotation scheme that is too complicated will not be followed. We describe the simple ones that are.
The slide that was not in the abstract
Reported from the sessions, and from the two hours afterwards.
Independent analysis puts a BCH tirzepatide lot at 98.3%, against 94.9% on the certificate
The report states the gradient, the wavelength and the integration threshold, which is more than most.
SURMOUNT-2 misses on a secondary endpoint the coverage has not mentioned
A design note rather than a result: what the comparator was, and what that permits you to conclude.
The certificate says 2024. The vial in your hand does not say anything.
The interval between manufacture and analysis is the most under-read figure on the page, and the one most likely to matter by the time a vial is opened.
Dose-limiting: a definition worth being strict about
Roughly four to seven per cent of trial participants discontinued for adverse events, mostly gastrointestinal, mostly during escalation. That is the empirical size of the…
Inspectors cite the consolidator trading as Meridian Freight Partners over sterility assurance
The observation that closes a facility is rarely the dramatic one.
Holograms, QR codes and other things that are not verification
Reported from the analysis, not from a warning notice.
What a 41% rise in coupling-reagent prices does to a 10 mg vial
Follow the resin, not the catalogue.
A supplier suspends shipping to Australia after 23 consecutive customs detentions
The route did not close because of a rule about peptides.
Seasonal use, holiday use, and the honest state of the evidence
A great deal of practice has grown up around intermittent schedules. The randomised evidence for any of them is, as far as the Journal can establish, nil.
A named analyst is the cheapest quality signal in this trade
What the Journal asks when a document arrives unsigned, and what the answers have been.
Portugal declines to reimburse dulaglutide outside a specialist service
Efficacy was never the question in this appraisal. Duration of treatment was.
Halvard & Pike Apothecary of Portland, Maine closes after 20 years
A proper account of an operation that existed, and of what closing it cost.
Why summer is a documented quality problem in this trade
The route did not close because of a rule about peptides.
Why summer is a documented quality problem in this trade
The route did not close because of a rule about peptides.