What twenty companies say about storage, and what they have measured
A retest date says that material should be re-examined before use. An expiry date says it should not be used. The trade uses the second word for the first concept.
The archive
Page 168 of 170 of this archive, newest first.
PeptideMeter result on a Guangzhou semaglutide lot lands 1.0 points below the supplier’s figure
The Journal submitted the sample and paid for the analysis. The vendor was told in advance.
Inspectors cite the relabeller trading as Vantris Bio over sterility assurance
The observation that closes a facility is rarely the dramatic one.
What the new Argentina guidance says about stopping
The evidence base is thin and the document says so, which is to its credit.
Suzhou export categories for peptide intermediates were quietly renamed
Follow the resin, not the catalogue.
What orthogonal actually means, and what it does not
The most useful single addition to any purity determination is a second separation under a different pH or on a different stationary phase, and the second-most useful is a…
Calder Vale Peptides of Skipton enters a consent decree and stops sterile preparation
The observation that closes a facility is rarely the dramatic one.
Sweden pharmacy body issues counselling standards for semaglutide initiation
The evidence base is thin and the document says so, which is to its credit.
REWIND extension data: what happens after the trial stops
A design note rather than a result: what the comparator was, and what that permits you to conclude.
Sending the same vial twice, under two names
Two years ago we ran an anonymised version of this comparison and promised a named one. This is it, with every method printed in full.
D-amino acids are invisible to mass spectrometry, and that is the whole problem
Stereochemical inversion changes the molecule, changes its biology, and changes its mass by exactly nothing.
Italy pharmacy body issues counselling standards for dulaglutide initiation
The evidence base is thin and the document says so, which is to its credit.
The slide that was not in the abstract
Reported from the sessions, and from the two hours afterwards.
QYB declines, for the 13th time, to name its synthesis house
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
New Zealand health authority warns on falsified tirzepatide pens
Reported from the analysis, not from a warning notice.
The shortage years, and what they taught about interruption
Real-world persistence figures, with their definitions stated, because the definitions are doing most of the work.
What a 1 mL syringe does that a 0.3 mL syringe does not
Dead space in the needle hub is a real and calculable loss, and it matters more at small volumes than anybody expects.
Why summer is a documented quality problem in this trade
The route did not close because of a rule about peptides.
Inspectors cite Halvard & Pike Apothecary of Portland, Maine over sterility assurance
The observation that closes a facility is rarely the dramatic one.
VendorInvestigate result on a Xi'an retatrutide lot lands 1.1 points below the supplier’s figure
The supplier has not disputed the finding. It has not explained the gap either.
What changed at WXT in January, and what the company will not say about it
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
Continuous monitoring changed the question and not the assay
HbA1c integrates roughly three months of glycaemia with the most recent weeks weighted most heavily. Almost every misreading of it is a misreading of that weighting.
Low endotoxin recovery: the interference nobody looks for
We submitted vials for endotoxin determination and report the results, the method and the laboratory, because a pyrogen figure without a method is as empty as a purity…
The quiet end of the relabeller trading as Vantris Bio
A proper account of an operation that existed, and of what closing it cost.
Independent analysis puts a BCH cagrilintide lot at 96.6%, against 93.4% on the certificate
The result is unremarkable. What the report omits is not.
CPC declines, for the 14th time, to name its synthesis house
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
Pancreatitis, obstruction, gallbladder: three things nausea can be
Pancreatitis is rare, was adjudicated in the outcome programmes, and did not show the imbalance early case reports suggested.
The eighteenth month, and the conversation that should have happened in the third
Weight reduction in the long programmes flattens at roughly sixty to seventy-two weeks. The timing is consistent, predictable and almost never mentioned in advance.
Two documents, two disciplines: purity and sterility are not the same trade
Every certificate circulating in this market answers a question about molecules. Almost none answers a question about organisms, pyrogens, or the integrity of the seal.
South Korea caps dulaglutide prescribing to 4 specialist centres
Efficacy was never the question in this appraisal. Duration of treatment was.