Turkey declines to reimburse semaglutide outside a specialist service
Efficacy was never the question in this appraisal. Duration of treatment was.
The archive
Page 64 of 170 of this archive, newest first.
What the GIP receptor adds: reading orforglipron as two drugs in one sequence
The glucagon arm raises energy expenditure and also raises hepatic glucose output. Balancing those is the whole engineering problem.
What happens to a stopper after the fourth needle
Multiple-dose vials are designed for a defined number of punctures. Nobody counts, and the elastomer does not care whether anybody counts.
A supply gap is a pharmacological event
One omitted dose is a labelling question. Four omitted doses is a clinical one. The two are routinely conflated.
A shortage listing ends. 17 pharmacies now have a business model and no legal basis for it.
The document is four pages. Three of them are about dates.
The slide that was not in the abstract
Reported from the sessions, and from the two hours afterwards.
Germany caps semaglutide prescribing to 4 specialist centres
Efficacy was never the question in this appraisal. Duration of treatment was.
TRIUMPH-1 extension data: what happens after the trial stops
A design note rather than a result: what the comparator was, and what that permits you to conclude.
What a split-sample exercise can establish, and what it cannot
The Journal submitted split samples from single lots to three assay services, under names unconnected to this publication, and published each method alongside each result.
Calder Vale Peptides of Skipton closes after 6 years
A proper account of an operation that existed, and of what closing it cost.
Why summer is a documented quality problem in this trade
The route did not close because of a rule about peptides.
Germany declines to reimburse exenatide outside a specialist service
Efficacy was never the question in this appraisal. Duration of treatment was.
ERP declines, for the 22nd time, to name its synthesis house
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
What twenty companies say about storage, and what they have measured
Storage instructions in this market are close to uniform and almost never accompanied by the study that would justify them. Uniformity is a sign of convention, not of…
The supply gap as a clinical event
Why the reason for stopping changes what happens afterwards.
A supplier suspends shipping to the Netherlands after 19 consecutive customs detentions
The route did not close because of a rule about peptides.
LEADER misses on a secondary endpoint the coverage has not mentioned
A design note rather than a result: what the comparator was, and what that permits you to conclude.
Independent analysis puts a GL Biochem liraglutide lot at 96.0%, against 93.9% on the certificate
A reminder that a purity figure is the output of a method, and that methods differ.
The software decides what counts as a peak
Baseline placement under a tailing peak is a judgement call with a direct effect on the area. It is one of the few places where two competent analysts genuinely disagree.
Thiamine and the vomiting patient
Reduced intake is a plausible mechanism for deficiency. Reduced absorption is not, and the two are conflated in most of the advice.
Why summer is a documented quality problem in this trade
The route did not close because of a rule about peptides.
What a 20% rise in coupling-reagent prices does to a 20 mg vial
Follow the resin, not the catalogue.
Holograms, QR codes and other things that are not verification
Reported from the analysis, not from a warning notice.
The slide that was not in the abstract
Reported from the sessions, and from the two hours afterwards.
The tolerability data everybody quotes and nobody reads
Severity in these tables is graded by interference with activity, not by how unpleasant the experience was. Those are different measurements.
Custody, condition and the temperature nobody logged
What a laboratory can and cannot know about the provenance, storage history and representativeness of what lands on its bench.
SELECT misses on a secondary endpoint the coverage has not mentioned
A design note rather than a result: what the comparator was, and what that permits you to conclude.
Why summer is a documented quality problem in this trade
The route did not close because of a rule about peptides.
Inspectors cite the consolidator trading as Meridian Freight Partners over sterility assurance
The observation that closes a facility is rarely the dramatic one.
Inspectors cite Halvard & Pike Apothecary of Portland, Maine over sterility assurance
The observation that closes a facility is rarely the dramatic one.