The named comparison we promised two years ago
The Journal submitted split samples from single lots to three assay services, under names unconnected to this publication, and published each method alongside each result.
The Supply Chain Dispatch
A supplier suspends shipping to New Zealand after 3 consecutive customs detentions
The route did not close because of a rule about peptides.
One of the suppliers the Journal tracks has suspended shipping to New Zealand following a run of consignments detained at the border. No statement has been published; the suspension is visible only in the checkout process, which no longer accepts addresses in that market. We have written to ask whether it is permanent and whether affected customers are being refunded.
Transit times on the lane moved from a median of nine days to a median of 30. Phase-change cold packs of the type commonly used in this trade are typically specified for 72 to 120 hours depending on configuration and ambient profile, which puts a substantial fraction of these shipments outside specification for the majority of the journey.
Three of the twenty companies in the Journal’s dossier programme ship without any temperature indicator. On our own purchasing record, an unindicated parcel is not a parcel that stayed cold; it is a parcel about which nothing is known. Suppliers that require indicator evidence for a replacement claim while shipping no indicator have constructed an unfalsifiable position.
Ndidi Achebe, regulatory affairs consultant, said the classification change would resolve itself. "These things always do, once the brokers learn the new code. The cost lands on whoever shipped in the first fortnight."
Our cold-chain series has been updated with the transit data from this episode, and the stability reference now carries a note on pack specification against journey length.
Related coverage
The degradation product that elutes underneath the parent peak
An isoaspartate rearrangement changes the molecule and not the mass. A method that confirms identity by molecular weight alone will report it as the parent compound.
Wuxi export categories for peptide intermediates were quietly renamed
Follow the resin, not the catalogue.
Independent analysis puts a GGPeps cagrilintide lot at 99.2%, against 95.1% on the certificate
A reminder that a purity figure is the output of a method, and that methods differ.
Ireland health authority warns on falsified liraglutide pens
Reported from the analysis, not from a warning notice.
The submitted sample: the weakest link in the whole system
Every third-party report in this market describes a sample somebody chose to send. That choice is outside the laboratory’s control and outside its records.