The supply gap as a clinical event
Real-world persistence figures, with their definitions stated, because the definitions are doing most of the work.
TheCompound Journal
Reporting on incretins, compounding & the peptide supply chain
The Ledger Dispatch
Efficacy was never the question in this appraisal. Duration of treatment was.
New Zealand has declined to reimburse semaglutide in general practice, restricting supply to specialist weight-management services. The appraisal accepted the clinical evidence and turned instead on the cost-effectiveness of an indefinite treatment duration in a population the size of the eligible one.
The carve-out removes cover for approximately 17,000 covered lives with 24 days’ notice. Employees already in treatment are offered a transition period; those in the middle of a titration are not distinguished from those at maintenance dose, which the Journal has asked about.
The carve-out removes cover for approximately 17,000 covered lives with 24 days’ notice. Employees already in treatment are offered a transition period; those in the middle of a titration are not distinguished from those at maintenance dose, which the Journal has asked about.
The structural feature of this market is that the list price and the price actually paid are different numbers, and that the second is contractually confidential in most systems. Any comparison of what a drug costs across countries that relies on published prices is comparing publications. The Journal reports both where it can and says which is which.
Rowena Ashcombe, community pharmacist and diabetes educator, said the duration assumption was doing all the work. "Change the assumed treatment length and the recommendation flips. That is not a criticism of the model; it is what the model is for."
We will follow the re-authorisation reviews, which is where the response criterion begins to bite, and which no published dataset currently covers.
Real-world persistence figures, with their definitions stated, because the definitions are doing most of the work.
Reported from the sessions, and from the two hours afterwards.
Cost is the modal reason for discontinuation in every dataset we have seen, and it is absent from the clinical literature.
Reported from the sessions, and from the two hours afterwards.
Efficacy was never the question in this appraisal. Duration of treatment was.
Efficacy was never the question in this appraisal. Duration of treatment was.