VendorInvestigate result on a Suzhou liraglutide lot lands 4.2 points below the supplier’s figure
The report states the gradient, the wavelength and the integration threshold, which is more than most.
Analytics in 2024
Page 4 of 10 of this archive, newest first.
Independent analysis puts a SGN survodutide lot at 96.5%, against 95.8% on the certificate
The result is unremarkable. What the report omits is not.
Before anything is weighed, the peptide has to be charged
A brief and unromantic tour of the interface between a liquid sample and a vacuum.
PeptideMeter result on a Guangzhou cagrilintide lot lands 3.7 points below the supplier’s figure
The result is unremarkable. What the report omits is not.
The question no chromatogram has ever answered
The Journal has read several hundred certificates from twenty companies. We set out what the documents actually cover, and what a reader is filling in from imagination.
The badge is about a sample. The listing is about a product.
Every step between the laboratory report and the product page removes information, and the badge is the last step.
Twenty-eight days is a number from somebody else’s product
Bacteriostatic water contains benzyl alcohol at 0.9 per cent, which inhibits microbial growth in a preserved multiple-dose presentation. It does not sterilise a contaminated…
Independent analysis puts a JEEP tirzepatide lot at 96.0%, against 92.6% on the certificate
The result is unremarkable. What the report omits is not.
LAL, kinetic chromogenic, recombinant factor C: three ways to the same figure
The limit for a parenteral product is calculable from the dose and the body weight in two lines. Almost nobody in this trade performs the calculation.
Independent analysis puts a JEEP semaglutide lot at 98.0%, against 96.9% on the certificate
The supplier has not disputed the finding. It has not explained the gap either.
Medutest result on a Changsha survodutide lot lands 4.3 points below the supplier’s figure
A reminder that a purity figure is the output of a method, and that methods differ.
A named analyst is the cheapest quality signal in this trade
What the Journal asks when a document arrives unsigned, and what the answers have been.
Independent analysis puts a SSA retatrutide lot at 95.4%, against 93.5% on the certificate
The supplier has not disputed the finding. It has not explained the gap either.
VendorInvestigate result on a Hong Kong dulaglutide lot lands 3.1 points below the supplier’s figure
The Journal submitted the sample and paid for the analysis. The vendor was told in advance.
Electrospray, MALDI, and the choice that shapes every spectrum after it
A brief and unromantic tour of the interface between a liquid sample and a vacuum.
We split six vials four ways and posted them
The Journal submitted split samples from single lots to three assay services, under names unconnected to this publication, and published each method alongside each result.
The empty half of every certificate of analysis
Purity, content, identity, sterility and endotoxin are five separate determinations. A single sheet of paper carrying one of them is not evidence about the other four.
PeptideMeter result on a Wuhan dulaglutide lot lands 1.8 points below the supplier’s figure
The supplier has not disputed the finding. It has not explained the gap either.
Independent analysis puts a TFC mazdutide lot at 98.1%, against 94.2% on the certificate
The report states the gradient, the wavelength and the integration threshold, which is more than most.
What the sequence tells you about how a peptide will fail
Reversed-phase chromatography runs in an organic, acidic mobile phase that dissociates most non-covalent aggregates on the way to the detector.