Why summer is a documented quality problem in this trade
The route did not close because of a rule about peptides.
Cold chain
Page 2 of 15 of this archive, newest first.
A supplier suspends shipping to Italy after 15 consecutive customs detentions
The route did not close because of a rule about peptides.
The retest date and the expiry date are not the same document
A retest date says that material should be re-examined before use. An expiry date says it should not be used. The trade uses the second word for the first concept.
Oxidation, and the peroxide that came in with the surfactant
We describe each pathway in enough chemical detail to explain why it is invisible to the method the trade uses, because that is the part which has practical consequences.
A supplier suspends shipping to Saudi Arabia after 15 consecutive customs detentions
The route did not close because of a rule about peptides.
Why summer is a documented quality problem in this trade
The route did not close because of a rule about peptides.
Why summer is a documented quality problem in this trade
The route did not close because of a rule about peptides.
A supplier suspends shipping to Singapore after 19 consecutive customs detentions
The route did not close because of a rule about peptides.
A supplier suspends shipping to Switzerland after 17 consecutive customs detentions
The route did not close because of a rule about peptides.
The degradation product that elutes underneath the parent peak
The sequence predicts the failure mode. A methionine predicts oxidation; an asparagine followed by a glycine predicts deamidation; a cysteine predicts disulphide scrambling.
Why summer is a documented quality problem in this trade
The route did not close because of a rule about peptides.
A supplier suspends shipping to India after 17 consecutive customs detentions
The route did not close because of a rule about peptides.
Why summer is a documented quality problem in this trade
The route did not close because of a rule about peptides.
Why summer is a documented quality problem in this trade
The route did not close because of a rule about peptides.
Why summer is a documented quality problem in this trade
The route did not close because of a rule about peptides.
A supplier suspends shipping to Norway after 5 consecutive customs detentions
The route did not close because of a rule about peptides.
A supplier suspends shipping to New Zealand after 3 consecutive customs detentions
The route did not close because of a rule about peptides.
Freezing a reconstituted vial: the ice-water interface problem
An in-use period is established by a dedicated study on a specific formulation in a specific container at a specific concentration. Borrowing one from a marketed product is…
Why summer is a documented quality problem in this trade
The route did not close because of a rule about peptides.
What freeze-drying actually removes, and what it leaves behind
Lyophilisation does not stop degradation. It slows every pathway by removing the solvent that most of them require, and the residue of solvent that remains sets the rate.