What changed at JEEP in January, and what the company will not say about it
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
Purity
Page 11 of 51 of this archive, newest first.
WXT declines, for the 16th time, to name its synthesis house
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
Spain health authority warns on falsified exenatide pens
Reported from the analysis, not from a warning notice.
What changed after we published the first version of this
None of what this piece asks for is commercially sensitive, and all of it is already known to whoever released the batch.
Independent analysis puts a SSA semaglutide lot at 97.6%, against 94.1% on the certificate
The Journal submitted the sample and paid for the analysis. The vendor was told in advance.
Leucine, isoleucine, and a difference no balance can measure
Stereochemical inversion changes the molecule, changes its biology, and changes its mass by exactly nothing.
Holograms, QR codes and other things that are not verification
Reported from the analysis, not from a warning notice.
Sending the same vial twice, under two names
Duplicate submissions under different names test within-laboratory repeatability, which is a different quantity from between-laboratory reproducibility.
Holograms, QR codes and other things that are not verification
Reported from the analysis, not from a warning notice.
What the four services actually offer, test by test
A compendial sterility test takes fourteen days of incubation and consumes the containers tested. That timescale is incompatible with the business model that made…
Six words a verification badge would need to mean anything
A badge asserts that something was tested. It does not assert what, when, on whose sample, by what method, or whether the lot on sale is the lot that was tested.
What twenty companies say about storage, and what they have measured
Storage instructions in this market are close to uniform and almost never accompanied by the study that would justify them. Uniformity is a sign of convention, not of…
Argentina health authority warns on falsified dulaglutide pens
Reported from the analysis, not from a warning notice.
We split six vials four ways and posted them
Two years ago we ran an anonymised version of this comparison and promised a named one. This is it, with every method printed in full.
A mass on a WWB certificate is a beginning, not a conclusion
What a single-stage mass measurement supports, what it excludes, and the gap between the two.
QYB declines, for the 17th time, to name its synthesis house
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
Tandem mass spectrometry, and the difference between weighing and reading
An intact mass measurement establishes elemental composition, at best. The number of distinct sequences consistent with a given composition is astronomically large.
The badge is about a sample. The listing is about a product.
Lot-level verification with a public report is a real and achievable thing. It exists in this market, on a minority of listings.
Two decimal places, one injection, no procedure
This piece takes the measurement apart into the decisions it is made of, because each decision moves the answer.
Medutest result on a Tianjin exenatide lot lands 2.1 points below the supplier’s figure
A reminder that a purity figure is the output of a method, and that methods differ.