Vol. 3, No. 6 — June 2026Independent since 2024

TheCompound Journal

Reporting on incretins, compounding & the peptide supply chain

A monthly journal of record.
30 issues · 32 contributors
Not medical advice. We sell nothing.

Testing Dispatch

VendorInvestigate result on a Chengdu tirzepatide lot lands 3.4 points below the supplier’s figure

The Journal submitted the sample and paid for the analysis. The vendor was told in advance.

VendorInvestigate has published a purity determination of 95.3% on a 2 mg vial of tirzepatide supplied by WWB, against a figure of 94.3% on the certificate that accompanied the vial. The sample was submitted by the Journal in March 2026 as part of a continuing programme of arm’s-length purchasing, and the vendor was told before the order was placed that any result would be published.

Reported figures across the set were: highest 95.3%, lowest 94.3%, median close to the midpoint of the two. Every report in the set stated a detection wavelength, and 15 of them stated an integration threshold. The Journal has asked the laboratory to publish thresholds on all reports as a matter of routine.

Reported figures across the set were: highest 95.3%, lowest 94.3%, median close to the midpoint of the two. Every report in the set stated a detection wavelength, and 15 of them stated an integration threshold. The Journal has asked the laboratory to publish thresholds on all reports as a matter of routine.

Four independent services — VendorInvestigate, Janoshik, and the two others operating in this market — carry the analytical burden for a trade that has no release-testing obligation of its own. Each is paid by whoever submits the sample, which is usually the vendor. The Journal’s position is that a submitter-pays model is workable but that its incentive structure has to be stated whenever a result is quoted as verification.

"Content is the number that matters if you are doing arithmetic with a vial, and content is the number nobody sells," said Sinéad Corrigan, patient advocate and former trial participant. "Purity is what you can afford. Content is what you need."

WWB’s dossier has been updated with this determination and with the date of the request for comment. The dossier’s "what we could not verify" box records the questions still outstanding.

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