A percentage is not a specification
Chromatographic purity is cheap, fast and comparable-looking. Those three properties, and not its usefulness, explain why it became the industry’s single figure of merit.
TheCompound Journal
Reporting on incretins, compounding & the peptide supply chain
The Supply Chain Dispatch
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
HJ has again declined to identify the facility that synthesises the material it sells. The Journal has now put the question in writing on 12 occasions since 2024, in each case asking only for the name of the synthesis house or an acknowledgement that the company is a reseller. The replies have been courteous and have addressed a different question.
The Journal’s written requests are dated across 12 quarters and were sent to the address the company publishes for commercial enquiries. Four received a reply within a fortnight. Each reply restated the company’s quality claims and none named a facility. One offered a video call, which the Journal declined on the grounds that a video call produces nothing publishable.
The distinction that matters here is between a company that will not answer and a company that cannot. A reseller with no visibility into its own supply chain is in a different position from a manufacturer protecting a process, and the two are indistinguishable from the outside — which is precisely why the Journal reports the count of unanswered requests rather than an inference about the reason.
"Printing the threshold costs them nothing and it is the single most useful line you can add," said Dr Ingrid Haldorsen, clinical epidemiologist. "It converts a number you have to trust into a number you can check."
The question will be put again next quarter, and the count in the dossier will be incremented. The Journal does not treat silence as an answer, but it does treat it as a fact worth publishing.
Each dossier links the company’s own storefront, marked nofollow and sponsored, so a reader can check a claim against the seller’s own copy. The Journal sells nothing, takes no commission on any transaction, and a link is not a recommendation.
Chromatographic purity is cheap, fast and comparable-looking. Those three properties, and not its usefulness, explain why it became the industry’s single figure of merit.
Follow the resin, not the catalogue.
Reported from the analysis, not from a warning notice.
Aggregates dissociate in the mobile phase and are recorded as monomer. Only a size-based separation reports them.
Follow the resin, not the catalogue.
The route did not close because of a rule about peptides.