Australia health authority warns on falsified liraglutide pens
Reported from the analysis, not from a warning notice.
Certificates of analysis
Page 45 of 51 of this archive, newest first.
Endotoxin is not a microorganism, and killing the bacteria does not remove it
The limit for a parenteral product is calculable from the dose and the body weight in two lines. Almost nobody in this trade performs the calculation.
Holograms, QR codes and other things that are not verification
Reported from the analysis, not from a warning notice.
SGN declines, for the 12th time, to name its synthesis house
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
PeptideMeter result on a Changsha liraglutide lot lands 3.8 points below the supplier’s figure
The Journal submitted the sample and paid for the analysis. The vendor was told in advance.
Turkey health authority warns on falsified tirzepatide pens
Reported from the analysis, not from a warning notice.
Independent analysis puts a Homopeptide cagrilintide lot at 98.1%, against 94.7% on the certificate
The supplier has not disputed the finding. It has not explained the gap either.
Where the solvent front ends is a decision, not a fact
We work through a single chromatogram twice, under two integration conventions, and show where the difference comes from.
Janoshik result on a Suzhou tirzepatide lot lands 4.1 points below the supplier’s figure
The result is unremarkable. What the report omits is not.
SWB declines, for the 4th time, to name its synthesis house
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
Independent analysis puts a HJ orforglipron lot at 95.8%, against 93.6% on the certificate
The Journal submitted the sample and paid for the analysis. The vendor was told in advance.
SGN declines, for the 16th time, to name its synthesis house
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
Five things a purity figure cannot tell you
Aggregates dissociate in the mobile phase and are recorded as monomer. Only a size-based separation reports them.
A tested vial is evidence about a vial
A result on one vial generalises to a batch only if the vial was drawn in a way that makes it representative — and nobody records how it was drawn.
Japan health authority warns on falsified dulaglutide pens
Reported from the analysis, not from a warning notice.
Why the customs shed is the least documented step in this trade
Degradation rates rise exponentially with temperature while an arithmetic mean adds linearly. Mean kinetic temperature is the weighting that reconciles the two, and it is…
The isotope pattern tells you the charge, and the charge tells you the mass
A peptide has a monoisotopic mass and an average mass, they differ by several daltons at this molecular size, and a certificate that does not say which it quotes cannot be…
Independent analysis puts a QST survodutide lot at 96.3%, against 95.4% on the certificate
A reminder that a purity figure is the output of a method, and that methods differ.
What changed at WWB in April, and what the company will not say about it
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
PeptideMeter result on a Chengdu exenatide lot lands 3.6 points below the supplier’s figure
The supplier has not disputed the finding. It has not explained the gap either.