What column temperature does to selectivity
Column chemistry, particle size and pore diameter determine what the separation is capable of before the gradient is even programmed.
Certificates of analysis
Page 49 of 51 of this archive, newest first.
GL Biochem names the synthesis and fill sites behind its catalogue
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
Quadrupole, time-of-flight, orbital trap: what each class can and cannot see
Every instrument specification quoted in an advertisement is a best case obtained on a calibration mixture, not on a submitted vial.
Independent analysis puts a QYB survodutide lot at 95.9%, against 94.3% on the certificate
The supplier confirmed the determination and supplied the method behind its own figure inside a week.
Holograms, QR codes and other things that are not verification
Reported from the analysis, not from a warning notice.
What a laboratory knows about the material it receives
The condition on arrival is recorded by some services and not others, and it is one of the more informative lines in a report.
In-use stability is a separate study, and almost nobody has done it
An in-use period is established by a dedicated study on a specific formulation in a specific container at a specific concentration. Borrowing one from a marketed product is…
Independent analysis puts a SSA exenatide lot at 97.3%, against 93.3% on the certificate
The supplier confirmed the determination and supplied the method behind its own figure inside a week.
Holograms, QR codes and other things that are not verification
Reported from the analysis, not from a warning notice.
Janoshik, Medutest, PeptideMeter, VendorInvestigate: a capability audit
The absence of microbiological capability in this market is a commercial fact with a straightforward explanation, and it is worth understanding before blaming anybody for it.
What changed at SSA in February, and what the company says prompted it
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
Singapore health authority warns on falsified semaglutide pens
Reported from the analysis, not from a warning notice.
What “LC-MS: conforms” tells a reader, which is almost nothing
None of what a checkable identity statement requires is commercially sensitive, and all of it is known to whoever produced the document.
Independent analysis puts a SSA semaglutide lot at 98.0%, against 94.0% on the certificate
The supplier confirmed the determination and supplied the method behind its own figure inside a week.
PeptideMeter result on a Qingdao cagrilintide lot lands 2.2 points above the supplier’s stated figure
A reminder that a purity figure is the output of a method, and that methods differ.
Set the threshold at a tenth of a per cent and the small impurities vanish
We work through a single chromatogram twice, under two integration conventions, and show where the difference comes from.
Holograms, QR codes and other things that are not verification
Reported from the analysis, not from a warning notice.
What changed at KP in February, and what the company says prompted it
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
Adsorption, and the dose that stayed on the glass
Every degradation pathway accelerates by orders of magnitude on reconstitution, because the solvent that lyophilisation removed is the reagent most of them need.
Norway health authority warns on falsified semaglutide pens
Reported from the analysis, not from a warning notice.