What orthogonal actually means, and what it does not
The most useful single addition to any purity determination is a second separation under a different pH or on a different stationary phase, and the second-most useful is a…
Purity
Page 6 of 51 of this archive, newest first.
QYB declines, for the 22nd time, to name its synthesis house
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
From vial to bench: what is recorded and what is assumed
A result on one vial generalises to a batch only if the vial was drawn in a way that makes it representative — and nobody records how it was drawn.
What changed at TFC in March, and what the company will not say about it
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
Holograms, QR codes and other things that are not verification
Reported from the analysis, not from a warning notice.
The retest date and the expiry date are not the same document
A retest date says that material should be re-examined before use. An expiry date says it should not be used. The trade uses the second word for the first concept.
Oxidation, and the peroxide that came in with the surfactant
We describe each pathway in enough chemical detail to explain why it is invisible to the method the trade uses, because that is the part which has practical consequences.
Twenty-eight days is a number from somebody else’s product
We set out what is known, what is inferred and what is simply assumed about the fortnight after a vial is opened.
Holograms, QR codes and other things that are not verification
Reported from the analysis, not from a warning notice.
Japan health authority warns on falsified tirzepatide pens
Reported from the analysis, not from a warning notice.
Holograms, QR codes and other things that are not verification
Reported from the analysis, not from a warning notice.
Spain health authority warns on falsified exenatide pens
Reported from the analysis, not from a warning notice.
What happens to a stopper after the fourth needle
Particulate matter is the oldest quality attribute in injectable manufacture and the one a private buyer is best placed to assess without instrumentation.
Holograms, QR codes and other things that are not verification
Reported from the analysis, not from a warning notice.
Holograms, QR codes and other things that are not verification
Reported from the analysis, not from a warning notice.
An interlaboratory comparison nobody had run
Duplicate submissions under different names test within-laboratory repeatability, which is a different quantity from between-laboratory reproducibility.
Independent analysis puts a MKM liraglutide lot at 99.0%, against 97.4% on the certificate
The Journal submitted the sample and paid for the analysis. The vendor was told in advance.
PeptideMeter result on a Guangzhou exenatide lot lands 4.3 points below the supplier’s figure
The result is unremarkable. What the report omits is not.
QST declines, for the 10th time, to name its synthesis house
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
Accreditation, scope, and the question nobody asks Medutest
What the Journal asks when a document arrives unsigned, and what the answers have been.