Medutest result on a Wuhan mazdutide lot lands 3.6 points below the supplier’s figure
The Journal submitted the sample and paid for the analysis. The vendor was told in advance.
The Supply Chain Dispatch
The United Kingdom health authority warns on falsified dulaglutide pens
Reported from the analysis, not from a warning notice.
The health authority in the United Kingdom has issued a warning on falsified dulaglutide injection pens found in the legitimate supply chain. The Journal has reviewed the notice and the accompanying photographs; the distinguishing features are a batch-number font difference and a needle-shield colour, neither of which a patient could reasonably be expected to detect.
Comparison of 10 certificates supplied by the reseller against the laboratory’s public archive matched 10 of them to reports commissioned by other parties, in some cases more than a year earlier. The reseller did not respond to two written requests for comment.
Comparison of 10 certificates supplied by the reseller against the laboratory’s public archive matched 10 of them to reports commissioned by other parties, in some cases more than a year earlier. The reseller did not respond to two written requests for comment.
The document is the weakest link in this trade. A certificate is a PDF; a laboratory letterhead is an image; a lot number is a string. Nothing in the ordinary transaction allows a buyer to confirm that a given report was issued for a given vial, and the four independent services differ in whether they offer any lookup at all.
Havel Novotný, independent laboratory quality manager, said the underfill finding was the more consequential one. "Nobody is being poisoned by a low content figure. Everybody using that vial is out by a fifth in every calculation they make."
Our series on identity confirmation covers the analytical detection of substitution in detail, including the mass differences that correspond to the commonest related compounds.
Related coverage
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Documentation practice is the only part of vendor quality a buyer can assess before purchase.
Everything on the page, in the order a chemist would read it
The header identifies the batch, the table records the tests, and the footer says who is answerable. Two of the three are usually incomplete.
Why a 0.036-dalton difference is the hardest number in peptide identity
Parts per million sound impressive until they are converted into daltons at the molecular weight of the thing being measured.
What a 20% rise in coupling-reagent prices does to a 5 mg vial
Follow the resin, not the catalogue.
What changed at SGN in January, and what the company will not say about it
Documentation practice is the only part of vendor quality a buyer can assess before purchase.